Snakemake
This is the development home of the workflow management system Snakemake. For general information, see
Python
— v9.9.0
— 12 Aug 2025
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WCI metadata
AiiDA
A workflow manager for computational science with a strong focus on provenance, performance and extensibility.
Python
— AiiDA v2.6.4
— 12 Aug 2025
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WCI metadata

Maestro Workflow Conductor
Orchestrate your HPC workflows with ease
Python
— v1.1.11
— 12 Aug 2025
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WCI metadata
Nextflow
A DSL for data-driven computational pipelines
Groovy
— Version 25.06.0-edge
— 12 Aug 2025
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WCI metadata
pyiron
A workflow manager for scientific computing on high performance computing infrastructures
python
— pyiron_base-0.13.4
— 11 Aug 2025
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WCI metadata

Cylc
A general purpose workflow engine with a particular gift for cycling.
Python
— cylc-flow-8.5.1
— 11 Aug 2025
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WCI metadata

Merlin
Enabling Machine Learning HPC Workflows
Python
— Version 1.13.0b2
— 10 Aug 2025
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WCI metadata
SciPipe
Robust, flexible and resource-efficient pipelines using Go and the commandline.
Go
— v0.12.0: Important bugfix. Minor API change.
— 09 Aug 2025
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WCI metadata

Swift/T
An MPI-based workflow system
Built with C; programmed with the Swift/T language
— 1.6.6
— 06 Aug 2025
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WCI metadata
PyCOMPSs/COMPSs
Easy task-based parallelization and efficient execution in distributed infrastructures.
Python, Java, C/C++
— 3.3.3 Orchid Update
— 02 Aug 2025
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WCI metadata

TaskVine
An execution system for large scale data intensive dynamic workflows.
Python
— devel
— 01 Aug 2025
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WCI metadata
SmartSim
Machine learning workflows with HPC applications (Python, C++, C, and Fortran)
Python
— 0.8.0
— 01 Aug 2025
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WCI metadata
Makeflow
Makeflow is a workflow system for parallel and distributed computing that uses a language very similar to Make.
Make
— devel
— 01 Aug 2025
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WCI metadata

nipype
Neuroimaging in Python: Pipelines and Interfaces
Python3
— 1.10.0
— 20 Jul 2025
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WCI metadata


Geoweaver
a lightweight workflow software to easily orchestrate pipelines from Python and shell scripts and preserve history of every execution
JavaScript
— v2.0.8
— 25 Jun 2025
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WCI metadata

DagOnStar
DAGonStar is a simple Python-based workflow engine that runs jobs on everything from the local machine to distributed virtual HPC clusters hosted in private and public clouds.
Python
— v1.0.2
— 27 May 2025
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WCI metadata
Apollo Runtime System
A runtime system for the orchestration of workflows across the cloud-edge-Iot continuum.
Polyglot for Functions, AFCL for workflows
— v1.1.0
— 13 Dec 2021
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WCI metadata
mlflow
The open source developer platform to build AI/LLM applications and models with confidence. Enhance your AI applications with end-to-end tracking, observability, and evaluations, all in one integrated platform.
Python — Nightly Build 2025-08-12 — 12 Aug 2025
toil
A scalable, efficient, cross-platform (Linux/macOS) and easy-to-use workflow engine in pure Python.
Python — 9.0.0 — 11 Aug 2025
cromwell
Scientific workflow engine designed for simplicity & scalability. Trivially transition between one off use cases to massive scale production environments
Scala — 90 — 11 Aug 2025
globus-compute
Globus Compute: High Performance Function Serving for Science
Python — 3.11.0 — 11 Aug 2025
pegasus
Pegasus Workflow Management System - Automate, recover, and debug scientific computations.
Java — 5.1.1 — 06 Aug 2025

For a comprehensive lists of all known computational workflow systems, see Computational Data Analysis Workflow Systems maintained by the CWL community.