Snakemake
This is the development home of the workflow management system Snakemake. For general information, see
Python
— v9.13.1
— 11 Oct 2025
— 
WCI metadata
pyiron
A workflow manager for scientific computing on high performance computing infrastructures
python
— pyiron_base-0.15.4
— 11 Oct 2025
—
WCI metadata
Nextflow
A DSL for data-driven computational pipelines
Groovy
— Version 25.09.1-edge
— 11 Oct 2025
—
WCI metadata
AiiDA
A workflow manager for computational science with a strong focus on provenance, performance and extensibility.
Python
— AiiDA v2.7.1
— 10 Oct 2025
—
WCI metadata
PyCOMPSs/COMPSs
Easy task-based parallelization and efficient execution in distributed infrastructures.
Python, Java, C/C++
— 3.3.3 Orchid Update
— 10 Oct 2025
—
WCI metadata
Cylc
A general purpose workflow engine with a particular gift for cycling.
Python
— cylc-flow-8.6.0
— 10 Oct 2025
—
WCI metadata
SmartSim
Machine learning workflows with HPC applications (Python, C++, C, and Fortran)
Python
— 0.8.0
— 07 Oct 2025
—
WCI metadata
nipype
Neuroimaging in Python: Pipelines and Interfaces
Python3
— 1.10.0
— 04 Oct 2025
—
WCI metadata
Merlin
Enabling Machine Learning HPC Workflows
Python
— Version 2.0.0b2
— 02 Oct 2025
—
WCI metadata
Makeflow
Makeflow is a workflow system for parallel and distributed computing that uses a language very similar to Make.
Make
— devel
— 01 Oct 2025
—
WCI metadata
TaskVine
An execution system for large scale data intensive dynamic workflows.
Python
— devel
— 01 Oct 2025
—
WCI metadata
Swift/T
An MPI-based workflow system
Built with C; programmed with the Swift/T language
— 1.6.6
— 26 Sep 2025
—
WCI metadata
Geoweaver
a lightweight workflow software to easily orchestrate pipelines from Python and shell scripts and preserve history of every execution
JavaScript
— v2.2.0-pre1
— 26 Sep 2025
—
WCI metadata
RADICAL-AsyncFlow
High Performance Asynchronous Workflow Scripting Library
Python
— 0.2.0
— 25 Sep 2025
—
WCI metadata
SciPipe
Robust, flexible and resource-efficient pipelines using Go and the commandline.
Go
— v0.12.0: Important bugfix. Minor API change.
— 24 Sep 2025
—
WCI metadata
DagOnStar
DAGonStar is a simple Python-based workflow engine that runs jobs on everything from the local machine to distributed virtual HPC clusters hosted in private and public clouds.
Python
— v1.0.2
— 18 Sep 2025
—
WCI metadata
Maestro Workflow Conductor
Orchestrate your HPC workflows with ease
Python
— v1.1.11
— 08 Sep 2025
—
WCI metadata
Apollo Runtime System
A runtime system for the orchestration of workflows across the cloud-edge-Iot continuum.
Polyglot for Functions, AFCL for workflows
— v1.1.0
— 13 Dec 2021
—
WCI metadata
mlflow
The open source developer platform to build AI/LLM applications and models with confidence. Enhance your AI applications with end-to-end tracking, observability, and evaluations, all in one integrated platform.
Python — v3.5.0rc0 — 11 Oct 2025
pegasus
Pegasus Workflow Management System - Automate, recover, and debug scientific computations.
Java — 5.1.1 — 10 Oct 2025
globus-compute
Globus Compute: High Performance Function Serving for Science
Python — 3.16.0 — 10 Oct 2025
cromwell
Scientific workflow engine designed for simplicity & scalability. Trivially transition between one off use cases to massive scale production environments
Scala — 91 — 10 Oct 2025
toil
A scalable, efficient, cross-platform (Linux/macOS) and easy-to-use workflow engine in pure Python.
Python — 9.1.1 — 05 Oct 2025
For a comprehensive lists of all known computational workflow systems, see Computational Data Analysis Workflow Systems maintained by the CWL community.